Peer-reviewed · Software-only · Implant-agnostic

The surgeon's engineering
department
for complex knee reconstruction

Send us the hard case: multi-ligament, revision, complex deformity. We turn the CT into a patient-specific 3D plan. Research use only.

Salnus is a research-use-only, software-only, implant-agnostic orthopaedic AI platform for preoperative surgical planning and clinical decision support.

OJSM
Published research
4-bone
CT segmentation
Browser
No install
Deep Learning Powered
Bone Segmentation
Personalized
Pre-operative Planning
Predictive Outcomes by
Geometrical Modeling
ANATOMICAL INTELLIGENCEAI Active
Anteroposterior weight-bearing knee radiograph with AI-generated biomechanical overlay showing joint space width measurement, mechanical axis alignment angles (LDFA, MPTA, FTA), and anatomical landmark detectionFLEFMElJSW5.4 mmmJSW5.1 mmLDFA88.1°MPTA87.3°FTA173.2°TTSALNUS · AI BIOMECHANICAL ANALYSISAI MODEL v2.4LDFA 88.1° · MPTA 87.3° · mJSW 5.1mm · FTA 173.2°KL-GRADE: 0
KL-0
Normal
5.1mm
Joint Space
END-TO-END PIPELINE

From CT to Surgical Plan

Example: complex multi-ligament knee reconstruction

And from the 3D model:

Tunnel Optimization & Analysis

AI-optimized tunnel trajectories with bone bridge safety analysis. 3D simulation and orthographic projections for multi-ligament knee reconstruction.

Automated Surgical Report

Complete surgical plan with landmark coordinates, anatomical measurements, protocol comparison, and risk analysis. PDF-ready clinical documentation.

app.salnus.com
Secure Surgeon Portal
DICOM Imaging
KVKK Compliant
Cloud Native
Tunnel feasibility analysis
Multi-Ligament Reconstruction Planning
Software-only, Implant-agnostic
OJSM-Published Research
Patient-Specific Surgical Guides (PSI)
AI Bone Segmentation
Preoperative 3D Planning
Runs in Your Browser
No Data Leaves Your Browser
KVKK-Compliant Infrastructure
Knee OA AI Analysis
Multi-Ligament Reconstruction Planning
Software-only, Implant-agnostic
OJSM-Published Research
Patient-Specific Surgical Guides (PSI)
AI Bone Segmentation
Preoperative 3D Planning
Runs in Your Browser
No Data Leaves Your Browser
KVKK-Compliant Infrastructure
Knee OA AI Analysis
Services

Clinical Intelligence
Platform

Cloud-native platform modules and professional services that standardise your preoperative planning, support surgical decision-making, and enable academic collaboration.

PLATFORM MODULES
LIVE BETA

Cloud-Based AI Platform

Secure DICOM viewing, AI-assisted analysis, and clinical reporting in one browser-based platform. No PACS integration or software installation required. Currently in invite-only beta.

DICOM viewer + AI analysis + reporting, one platform.SaaS · DICOM · MPR · Cloud · Invite-Only
LIVE BETA

Automated Surgical Reporting

AI-generated clinical reports from radiological measurements (JSW, MPTA, LDFA, FTA). Standardised PDF output with grading assessment, alignment analysis, and surgical recommendations.

From DICOM to PDF report in seconds.PDF · Reporting · Automated
MODEL READY

OA Intelligence Suite

AI-powered knee osteoarthritis grading. DenseNet-121 architecture trained on OAI dataset. Binary OA detection: 84.1% accuracy. Five-class KL grading: 70.3% accuracy. 21+ experiments completed. 27MB model, browser-inference ready.

Knee OA grading with deep learning.KL-Grade · JSW · OA · Deep Learning · DenseNet-121
BETA

Geometric Analysis & Measurement

Anatomical angle calculation (MPTA, LDFA, HKA, FTA), landmark detection, and mechanical axis alignment analysis. Interactive landmark placement with AI-assisted detection for streamlined workflow.

Auto angles + landmarks + axis alignment.MPTA · LDFA · HKA · Semi-Automated
Internal validation, manuscript in submission

Auto-Segmentation & 3D Modelling

Deep learning bone segmentation from knee CT, trained on a multi-center cohort. Four-bone segmentation across femur, tibia, patella, and fibula. Internal validation; manuscript in submission. Automated CT-to-3D mesh pipeline for surgical visualisation and PSI design.

AI bone segmentation + 3D mesh export.nnU-Net · 4-Bone · CT · STL · 3D Mesh
IN DEVELOPMENT

MRI Cartilage & Meniscus Segmentation

Deep-learning segmentation of bone, cartilage, and menisci from knee MRI. An nnU-Net model in development on a curated cohort, extending our CT segmentation pipeline to soft-tissue and cartilage assessment. Research stage, manuscript in preparation.

Bone + cartilage + meniscus segmentation from MRI.nnU-Net · MRI · Bone · Cartilage · Meniscus
MODEL READY

Multi-Ligament Reconstruction Planning

A software-only, automated optimizer for multi-ligament tunnel collision: not manual virtual planning, not hardware. Tunnel-angle optimization, bone-bridge safety analysis, and 3D tunnel visualization, from CT landmarks to a complete surgical plan. Grounded in our OJSM-published research.

Optimized tunnel angles + bone bridge safety analysis.Multi-Ligament · Knee · Tunnel Optimization · 3D Planning
PLANNED

Deformity Analysis & Correction Planning

Varus/valgus angle analysis, osteotomy simulation, and mechanical axis correction planning based on Paley principles. End-to-end preoperative deformity assessment for HTO and DFO candidates.

Mechanical axis restoration with digital precision.Deformity · HTO · DFO · Paley
PROFESSIONAL SERVICES
OJSM PUBLISHED

3D Modelling & Surgical Guides (PSI)

3D reconstructions precisely matched to the patient's anatomy. Surgical guide design for HTO, DFO, and specific osteotomies, maximising postoperative accuracy. Clinically validated and published in OJSM.

Patient-specific PSI; maximum axial alignment accuracy.3D Print · HTO · DFO · PSI

Technical Consultancy

Elite athlete surgical planning, complex deformity case analysis, and biomechanical modelling for challenging clinical scenarios. Expert-level support from biomedical engineers.

Case-by-case expert biomedical engineering support.Elite Athlete · Complex Cases · Biomechanics

Custom Orthopaedic Software

Bespoke clinical software tailored to your practice needs. From deformity correction algorithms to patient management tools, IP shared, revenue model negotiable.

Your clinical need, our engineering, shared IP.Bespoke · Shared IP · Revenue Share

Clinical & Academic Partnerships

Clinical dataset curation, algorithm co-development, and joint publication support for medical imaging research. Collaborative AI model training with shared academic output.

IP sharing, revenue-sharing or licensing model.R&D · Academic · Dataset · IP Sharing

Medical AI Training & Workshops

Hands-on training for surgeons on digital preoperative planning, AI-assisted analysis tools, and 3D surgical guide design. Congress workshops and institutional training programmes available.

Upskill your team in AI-assisted surgical planning.Training · Workshop · Congress · Education
Case Studies

Clinical Evidence

Clinical outcomes achieved by our models using real hospital data.

Published · OJSM 2026

3D-Printed Patient-Specific Guides for Knee Reconstruction

Our study published in The Orthopaedic Journal of Sports Medicine validated the clinical accuracy of 3D-printed patient-specific instrumentation (PSI) for knee reconstruction procedures, demonstrating significant improvement in intraoperative precision compared to conventional techniques.

OJSM
Publication
PSI
3D-Printed
Knee
Reconstruction
Completed · AI Model

Four-Bone Knee CT Segmentation Model

Custom nnU-Net deep learning model trained on a multi-center cohort of annotated knee CT volumes. Four-bone segmentation across femur, tibia, patella, and fibula; internal validation, manuscript in submission. The fibula is rarely segmented in dedicated knee CT work, making this a notable result.

0.964
Mean Dice, internal
4-Bone
nnU-Net
167
Patients
Under Review · Hip OA

Hip Osteoarthritis AI Analysis

Deep learning-based hip osteoarthritis detection and grading model. Systematic review and meta-analysis of 25 studies completed; original model development in progress.

Scientific Foundation

From Academic Research
to Clinical Application

Every module in our products is grounded in our own research, from peer-reviewed publications to studies currently under review.

Peer-Reviewed Publications & Ongoing Research

Active research portfolio, published, under review, and in development

OJSM, The Orthopaedic Journal of Sports Medicine
3D-Printed Patient-Specific Guides for Knee Reconstruction: A Clinical Study
Salnus · 2026
✓ Published · Open Access
Original Article
Deep Learning-Based Automated Grading Tool for Knee Osteoarthritis
Salnus · 2026
⟳ Under Review
PROSPERO-Registered Systematic Review
Artificial Intelligence in Hip Osteoarthritis: Systematic Review and Meta-Analysis
Salnus · 2026
⟳ Under Review
Original Research
nnU-Net-Based Four-Bone Knee CT Segmentation: Multi-Center Development and Validation
Salnus · 2026
⟳ Under Review
Systematic Review
Artificial Intelligence in Knee Osteoarthritis: Systematic Review of Detection, Grading, and Segmentation Models
Salnus · 2026
⟳ Under Review
Systematic Review & Meta-Analysis
AI for Osteonecrosis of the Femoral Head Detection on MRI: Systematic Review and Meta-Analysis
Salnus · 2026
⟳ Under Review
RESEARCH PIPELINE
IN DEVELOPMENT
Fracture Detection
IN DEVELOPMENT
ACL Tear Detection
IN DEVELOPMENT
Meniscus Tear Detection
Clinical & Academic Collaboration Models
01

Academic Partnership

AI for Knee OA grading, systematic meta-analyses, and deep learning model co-development. Clinical dataset curation and technical contribution to joint publication processes.

02

Custom Orthopaedic Software

Deformity correction planning software and 3D surgical guide design with shared IP ownership for your clinical needs. Revenue-sharing model.

03

Technical Consultancy

Elite athlete surgical planning, complex defect modeling via 3D printing, and DICOM-based AI infrastructure for your clinical workflow.

Platform Infrastructure
Python / PyTorchComputer VisionCloud InfrastructureEncrypted Data TransferDICOM SupportReact / TypeScriptPostgreSQLKVKK ✓Pre-operative AnalysisClient-Side AI Inference
The difference

Why Salnus

Software, not hardware. Vendor-neutral, not locked-in. In the browser, not the cloud.

Implant-agnostic

Not locked to a single manufacturer. Surgeons keep their implant choice.

Software-only

No hardware, no capital cost, no PACS integration.

Browser-based, client-side

Runs in the browser; patient images stay in the clinic (KVKK/GDPR-aligned).

Peer-reviewed foundation

Grounded in a peer-reviewed OJSM 2026 publication. Research-use-only (RUO).

Clinical Pilot, Limited Spots

Request
access to the pilot

Reserve early access to the Salnus orthopaedic AI clinical pilot. Surgeons, radiologists, and institutions can request a spot in the upcoming wave.

GDPR and KVKK compliant

Other inquiries: info@salnus.com

Orthopaedic AI Research Updates

Monthly research digest, product updates, and clinical AI insights.

Unsubscribe anytime.

Salnus, AI-Powered Orthopaedic Surgery Platform