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Multicenter Osteoarthritis Study (MOST)

MOST is a longitudinal study of knee osteoarthritis containing knee radiographs and MRI examinations collected across multiple clinical visits. Later study cycles also introduced knee CT measurements.

Licence and access

Access is managed through the NIA AgingResearchBiobank and requires registration, submission of a research request and acceptance of the applicable data-use conditions. Explicit permission or prohibition for commercial use could not be verified from the public study pages.

application requiredcommercial use unverifiedredistribution restricted
Visit official sourcelast verified 2026-09-09
Access status: Access requires an application, data-use agreement, registration workflow or institutional approval.
Coverage
kneeclassificationin vivo
subjects
3,026
images
not verified
formats
not verified
origin
not verified
Citation
Segal NA, Nevitt MC, Gross KD, et al. The Multicenter Osteoarthritis Study: opportunities for rehabilitation research. PM&R. 2013;5(8):647-654. DOI: 10.1016/j.pmrj.2013.04.014.
Notes

The original MOST cohort contained 3,026 participants. The official protocol reports that 2,600 participants had baseline MRI in at least one knee. A new cohort of 1,525 participants was added during the third cycle, so num_subjects represents the original cohort. The exact downloadable imaging formats and a stable total image count could not be verified.

This record is a pointer. Licence and access terms are recorded as they stood on the verification date above; what binds you is the dataset's own licence text. Confirm at the source before use.

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Multicenter Osteoarthritis Study (MOST), dataset record